|
• |
Subcutaneous blood flow (increased blood flow will give a faster insulin absorption)
• |
Increased by: Heat e.g. sauna, buble pool or fever.
|
• |
Decreased by: Cold e.g. a cold bath. Smoking (constriction of the blood vessels) Dehydration.
|
|
|
• |
Injection depth: Faster absorption after an intramuscular injection.
|
|
• |
Injection site: An abdominal injection will be absorbed faster than a thigh injection. The absorption from the buttocks is slower that the abdomen but faster than the thigh.
|
|
• |
Insulin antibodies: Can bind the insulin resulting in a slower and less predictable effect.
|
|
• |
Exercise: Increases the absorption of short-acting insulin even after the exercise is ended, particularly if the injection is given intramuscularly.
|
|
• |
Massage of the injection site: Increased absorption, probably due to a faster breakdown of the insulin.
|
|
• |
Subcutaneous fat thickness: A thicker layer of subcutaneous fat gives a slower absorption of insulin.
|
|
• |
Injection in fat lumps (lipohypertrophies): Slower and more erratic absorption of insulin.
|
|
• |
Concentration of the insulin: 40 U/ml. Is absorbed faster than 100 U/ml. |